PhD Search Results


  • Funded MD – Application Deadline: 2nd Jan 2018 – RCSI – Hermitage Medical Clinic StAR MD Programme 2018

    RCSI

    Principal Investigator: RCSI StAR MD Programme, RCSI

    Start Date: 02/07/2018

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    MD candidates are required to have obtained the degrees of MB BCh BAO and general or trainee specialist registration with the Irish Medical Council (www.medicalcouncil.ie).

    Applicants should liaise with potential supervisors to have agreed the focus of, and in broad outline the nature of, the research they wish to carry out. These MD places will be competitive.

    It is expected that interested applicants will have:

    • previously undertaken research or audit projects at undergraduate and/or postgraduate level,
    • presented at national or other meetings,
    • publications confirming the quality of this activity.
    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: Included in Funding (EEA*) Part Time: N/A

    (International/Non-EEA) Full Time: Included in Funding Part Time: N/A

    |

    Bench Fees Full Time: Included in Funding Part Time: N/A

    Project Summary

    RCSI is seeking submissions from interested physician candidates who wish to undertake a Doctorate in Medicine (MD) Degree Programme through the Strategic Academic Recruitment (StAR) Programme in the following research areas: Neurological and Psychiatric Disorders; Population and Health Systems; Regenerative Medicine (Bioengineering); Surgical Science and Practice; Translational Cancer; Vascular Biology; Respiratory Medicine; Gynaecology,...

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  • Funded PhD – Application Deadline 3rd January 2018 – The development of tissue-engineered models of the respiratory tract as an innovative tool for respiratory drug development & delivery and the basis for regenerative therapies

    RCSI

    Principal Investigator: Professor Sally-Ann Cryan, RCSI

    Start Date: 01/02/2018

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    The ideal applicant will have a 1st Class Honours Bachelor’s degree or MSc degree (with minimum 2.1 honours from primary degree) in pharmacy, biomedical engineering or related disciplines.

    Specific skills which would enhance a candidate’s application include experience in some of the following areas: materials science, scaffolds in tissue engineering, cell culture, RT-PCR, protein isolation and quantification, advanced microscopy, histological techniques and nanoparticle syntheses.

    Excellent written and oral communication skills are also desired.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: Included in Funding (EEA*) Part Time: N/A

    (International/Non-EEA) Full Time: €6,550 Part Time: N/A

    |

    Bench Fees Full Time: Included in Funding Part Time: N/A

    Project Summary

    The translation of new inhalable therapies for the treatment of respiratory disease and systemic drug delivery is being hampered by a lack of appropriate, validated and regulatory-approved in vitro drug development and disease models. The aim of this PhD project is to develop innovative models of the respiratory tract using tissue engineering strategies that...

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  • Funded PhD – Application Deadline 30 Nov 2017 – Paediatric brain tumours – Improving and personalising chemotherapy treatment options for paediatric brain tumour patients

    RCSI

    Principal Investigator: Dr Brona Murphy, RCSI

    Start Date: 01/01/2018

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    The successful candidate should be able to demonstrate the following:

    Essential

    • An Honours Bachelor degree (grade 2.1 or above) in Biochemistry, Molecular Biology, Bioinformatics, Computational Biology or a related discipline
    • Excellent written and oral communication skills
    • Strong self-motivation and organisational skills
    • Ability to work on one’s own initiative as well as in a multidisciplinary, team environment
    • Willingness to undertake training and career development
    • English language requirements (for non-native English speakers) is an IELTS (academic) score of 6.5 or above.

    Desirable:

    • Previous related research experience will be a distinct advantage.
    • Programming skills (MATLAB)

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: Included in Funding (EEA*) Part Time: Not Applicable

    (International/Non-EEA) Full Time: €6,550 Part Time: Not Applicable

    |

    Bench Fees Full Time: Included in Funding Part Time: Included in Funding

    Project Summary

    The aim of this project is to set an example for how innovative systems-level strategies can be exploited to address urgent clinical needs for developing predictive assays for existing drugs and new drug combinations.

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  • Funded PhD – Thrombosis and Vascular Biology – Contribution of platelet biomechanics to the functional diversity of platelets – Application Deadline: 1st December 2017

    RCSI

    Principal Investigator: Dr Ingmar Schoen, RCSI

    Start Date: 01/02/2018

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    The successful candidate should be able to demonstrate the following: Essential

    • An Honours Bachelor degree (grade 2.1 or above) in the natural sciences (biology, physics), bioengineering, or interdisciplinary study programmes
    • Open and direct communication
    • A high motivation to develop scientific thinking, experimental and problem-solving skills throughout the duration of the project
    • Ability to work on one’s own initiative and to organise yourself
    • Willingness to work together with scientists from different disciplines
    • English language requirements for candidates who do not speak English as their first language: an IELTS score of 6.5 or above

    Desirable:

    • Pre-experience with microscopy techniques, cell culture, or blood handling
    • Programming skills (MATLAB)

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: Included in Funding (EEA*) Part Time: Option not available

    (International/Non-EEA) Full Time: €6,550 Part Time: Option not available

    |

    Bench Fees Full Time: Included in Funding Part Time: Option not available

    Project Summary

    The aim of this PhD project is to better understand the heterogeneity within the platelet population. The primary emphasis will be on platelet contractility and related features (such as cytoskeletal morphology). The secondary aim is to correlate biomechanical with biochemical functions (such as platelet granule secretion or PS exposure) on the level of single...

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  • Funded PhD – PhD in Cancer Systems, Biology/BioInformatics

    RCSI

    Principal Investigator: Dr Darran O'Connor, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    The successful candidate should be able to demonstrate the following: Essential

    • BSc (grade 2.1 or above) in mathematics, applied mathematics, statistics or related subject with substantial quantitative component, e.g. physics, engineering, computer science
    • Excellent computational skills including experience of using statistical software packages, e.g. R, STATA or SAS
    • Extensive experience working in a Unix environment
    • Interest in applying mathematics to problems in health-related fields
    • Scientifically competent
    • Effective communication style – excellent English (for candidates who do not speak English as their first language: an IELTS (academic) score of 6.5 or above)
    • Strong organisational and administrative skills
    • Ability to make decisions and meet deadlines
    • Ability to work on one’s own initiative as well as in a multidisciplinary, team environment

    Desirable

    • MSc in systems biology or bioinformatics (or other relevant discipline)
    • Experience of programming in R, STATA, SAS, Python or C/C++
    • Experience with molecular networks in biology and their modelling

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: Included in Funding (EEA*) Part Time: Included in Funding

    (International/Non-EEA) Full Time: Included in Funding Part Time: Included in Funding

    |

    Bench Fees Full Time: Included in Funding Part Time: Included in Funding

    Project Summary

    The aim of this project is to develop a novel decision support tool for Her2+ breast cancer.

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  • Application deadline : 14 July 2017 – FUNDED project: Advanced scaffold based delivery system for nucleic acids through the incorporation of novel nanoparticles

    RCSI

    Principal Investigator: Professor Fergal O'Brien, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    The ideal applicants will have a 1st Class Honours Bachelor’s degree and/or MSc degree (with minimum 2.1 honours from primary degree) in biomedical engineering, regenerative medicine, pharmacy, relevant life sciences or related disciplines.

    Excellent written and oral communication skills are desired.

    Specific skills which would enhance a candidate’s application might include experience in some of the following areas: scaffolds in tissue engineering, nanoparticle formulation and characterisation, drug delivery, cell culture, histological techniques and molecular biology experience.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: Included in funding (EEA*) Part Time: N/A

    (International/Non-EEA) Full Time: Included in funding Part Time: N/A

    |

    Bench Fees Full Time: Included in funding Part Time: N/A

    Project Summary

    The aim of this project is to develop novel collagen-based scaffolds functionalised for the delivery of RNA-based therapeutics using nanoparticles recently developed by researchers based in the SFI-funded CÚRAM and AMBER centres. The scaffolds developed will be used as novel platforms for tissue regeneration, for in vitro disease modelling, and to study drug development...

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  • Application Deadline: 14 July 2017 – FUNDED: Development of advanced biomaterials for bone and cartilage regeneration

    RCSI

    Principal Investigator: Professor Fergal O'Brien, RCSI

    Start Date: 02/10/2017

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    The researchers will work closely with other members of a large multidisciplinary project team including PIs, clinicians, postdoctoral and postgraduate researchers in the Tissue Engineering Research Group at the Royal College of Surgeons in Ireland in partnership with the AMBER (Advanced Materials and BioEngineering Research) Centre. The ideal applicants will have a 1st Class Honours Bachelor’s degree and/or MSc degree (with minimum 2.1 honours from primary degree) in biomedical engineering, materials science, regenerative medicine, pharmacy, relevant life sciences or related disciplines.

    Excellent written and oral communication skills are desired.

    Specific skills which would enhance a candidate’s application might include experience in some of the following areas: scaffolds in tissue engineering, nanoparticle formulation and characterisation, cell culture & transfection with DNA/RNA, advanced microscopy and molecular biology experience

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: included in funding (EEA*) Part Time: N/A

    (International/Non-EEA) Full Time: included in funding Part Time: N/A

    |

    Bench Fees Full Time: included in funding Part Time: N/A

    Project Summary

    The aim of this project will be to enhance the bone and cartilage-forming potential of materials using DNA or RNA, to control mesenchymal stem cell hypertrophy.

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  • Application Deadline 14th July 2017 – FUNDED project: Investigating the role of rare, functional genetic variation on psychosis and mood disorders in epilepsy

    RCSI

    Principal Investigator: Dr Gianpiero Cavalleri, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: (EEA*) Part Time:

    (International/Non-EEA) Full Time: Part Time:

    |

    Bench Fees Full Time: Part Time:

    Project Summary

    This project will, building on analysis conducted by our research group in collaboration with others, explore the genetic component to psychosis as a co-morbidity of epilepsy, and as an adverse reaction to anti-epileptic drugs.

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  • Understanding the Role of the Biomolecules at the BioNano Interface

    RCSI

    Principal Investigator: Dr Marco Monopoli, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    The biomolecular corona gives a new identity to nanoparticles in biological milieu as it has been shown to directly interact with cellular receptors while the pristine surface remains buried while in this environment. This project is focused on understanding how these biomolecules control the biological fate of the nanomaterials in biological milieu and to explore...

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  • Inhibiting tumour growth using a novel anti-cancer protein, FKBPL

    RCSI

    Principal Investigator: Professor Tracy Robson, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    We have isolated and characterised a novel human gene, FKBPL, a divergent member of the immunophilin family of proteins. FKBPL, is emerging as a as a key player in the DNA damage response, steroid receptor signalling and control of tumour growth where it regulates response to endocrine therapy, acts as a novel anti-angiogenic protein...

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  • Provision of Smoking Cessation Care in Hospital Settings

    RCSI

    Principal Investigator: Dr Frank Doyle, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €3,000 Part Time: €2,000

    Project Summary

    Although receiving brief smoking cessation advice from healthcare professionals is known to increase smokers' quit attempts, such advice is not usually provided. This is usually due to factors such as time constraints, staff attitudes towards smoking and provision of advice, and lack of skills training. This project will develop and implement an intervention to...

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  • Attitudes to Organ Donation

    RCSI

    Principal Investigator: Dr Frank Doyle, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €3,000 Part Time: €2,000

    Project Summary

    Although most people are in favour of organ donation, a minority sign up for donation. This project will investigate cognitive and emotional factors that inhibit and enhance signing up for organ donation and discussing this with family members. We aim to design interventions to maximise donation.

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  • Network Meta Analysis of Psychological Factors Influencing Health Behaviours

    RCSI

    Principal Investigator: Dr Frank Doyle, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €3,000 Part Time: €2,000

    Project Summary

    Psychological factors such as attitudes and depression are known to be an important influence on health behaviours such as smoking or physical activity. However, little work has investigated the relative influence of these factors, and interventions usually target relatively few psychological aspects. To date, such interventions have not been comparable. The present project proposed...

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  • Depression and Health Behaviours in Chronic Conditions

    RCSI

    Principal Investigator: Dr Frank Doyle, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €3,000 Part Time: €2,000

    Project Summary

    The prevalence of depression is elevated in those with chronic conditions, and is often associated with poorer prognosis and lower adherence to recommended therapies. For example, in coronary disease and respiratory disease, those with elevated depressive symptoms are less likely to quit smoking, take their prescribed medications or increase their physical activity. The present...

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  • Adherence to Inhaled Therapies

    RCSI

    Principal Investigator: Dr Frank Doyle, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €3,000 Part Time: €2,000

    Project Summary

    Inhaled therapies are a cornerstone of treatments for common conditions such as asthma and chronic obstructive pulmonary disease. However, adherence to such therapy is known to be low and research has shown that such non-adherence can be both accidental and deliberate. The Inhaler Compliance Aid is unique in that it can identify not only...

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  • Psychometrics of Patient Reported Outcomes

    RCSI

    Principal Investigator: Dr Frank Doyle, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €3,000 Part Time: €2,000

    Project Summary

    Patient reported outcomes are a vital part of modern healthcare. However, commonly used measures do not always demonstrate sound psychometric qualities, and could be enhanced by omitting non-performing items. In other cases, the measures should be abandoned and other, more suitable ones adopted.

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  • Evaluation of Factors Influencing Success of Randomised Controlled Field Trials of Household Water Treatments in Developing Countries

    RCSI

    Principal Investigator: Professor Kevin McGuigan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Over the past 5 years the RCSI solar disinfection group has conducted a number of large scale randomised controlled field trials (RCTs) of solar water disinfection (SODIS) in several developing world locations such as Cambodia1 , South Africa2 , Zimbabwe and Uganda3. Similar RCTs have been attempted by other research groups elsewhere in India4And...

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  • Platelets as Orchestrators of inflammation in Airways Disease

    RCSI

    Principal Investigator: Dr Steve Kerrigan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    This project will investigate the platelet contribution to inflammation in patients with chronic obstructive pulmonary disease which includes asthma, bronchitis, emphysema and cystic fibrosis. Please include relevant information such as ethical approval; animal handling training;animal licensing; IP/commercialisation potential; up to 5 references; Respiratory disease is considered to be the third leading cause of life-threatening...

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  • Evaluating Transition Experiences, Social Connectedness and Self Efficacy Among Stroke Survivors

    RCSI

    Principal Investigator: Professor Frances Horgan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Physiotherapy Primary Degree, 2.1

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €3,000 Part Time: €2,000

    Project Summary

    Stroke is a leading cause of death and disability worldwide and it is estimated that cerebrovascular diseases account for up to 5 per cent of total health-care expenditure in a number of countries (Evers et al., 2004; Rossnagel et al., 2005). The rapid and sometimes dramatic changes caused by a stroke can be devastating...

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  • Real Time Live Epifluorescent Imaging of the Effects of Bacteria in the Bloodstream

    RCSI

    Principal Investigator: Dr Steve Kerrigan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Which undergraduate disciplines are relevant for this project :

    Cell Biology, Biochemistry, Pharmacology, Physiology, Genetics, Biophysics, Biotechnology,

    Microbiology

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    The Host Infection Group in RCSI headed by Dr. Kerrigan is interested in molecular mechanisms that exist between invading pathogens and host cells primarily focusing on Staphylococci and Streptococci interaction with human blood platelets, human endothelial cells (brain microvascular, aortic and peripheral veneous) and human bone cells (osteoblasts and osteoclasts).

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  • Gait Analysis in People with Hip Osteoarthritis: A Prospective Longitudinal Study

    RCSI

    Principal Investigator: Dr Helen French, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €5,000 Part Time: €3,300

    Project Summary

    Osteoarthritis (OA) is a degenerative joint disease characterised by progressive loss of cartilage. Walking is commonly limited, especially in advanced disease. Although gait deficits have been identified using three dimensional gait analysis (3DGA) in people with hip OA1 , there are no known studies that have used 3GDA to evaluate changes in gait over...

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  • Trespassing the Defensive Lines in Cardiovascular Infection

    RCSI

    Principal Investigator: Dr Steve Kerrigan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Undergraduate disciplines relevant for this project: Cell Biology, Biochemistry, Pharmacology, Physiology, Genetics, Biophysics, Biotechnology, Microbiology.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    The Host Infection Group in RCSI headed by Dr. Kerrigan is interested in molecular mechanisms that exist between invading pathogens and host cells primarily focusing on Staphylococci and Streptococci interaction with human blood platelets, human endothelial cells and human bone cells. S. aureus is a universal gram positive bacteria that lives harmlessly on the...

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  • Movement Analysis of Sports-related Hip and Groin Pain

    RCSI

    Principal Investigator: Dr Helen French, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €5,000 Part Time: €3,300

    Project Summary

    This research aims to investigate hip and knee biomechanics associated with sports-related hip and groin pain, using Vicon 3D motion analysis.

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  • An Innovative and Multi-disciplinary Systems Medicine Project to Case-specifically Optimise Anti-cancer Treatments

    RCSI

    Principal Investigator: Dr Markus Rehm, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Key to the personalisation of anti-cancer therapies are tools that allow to evaluate which drug treatments are likely to be effective. However, reliable markers for cancer cell responsiveness to chemotherapeutics often do not exist. Therefore, novel approaches that allow the prediction of drug responsiveness on a case-by-case basis are required. Impressive progress in this respect...

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  • Identifying Features of Central Sensitisation in People with Hip OA and the Impact of Targeted Therapy: a Mixed Methods Study

    RCSI

    Principal Investigator: Dr Helen French, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Undergraduate discipline relevant for this project: Physiotherapy

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €5,000 Part Time: €3,300

    Project Summary

    Osteoarthritis (OA) is a degenerative joint disease which commonly affects the hip joint. Although pain associated with hip OA is considered to be due to nociceptive damage at joint level, there is increasing evidence of features of central sensitisation, due to altered pain processing in the central nervous system. This has implications for pharmacological and...

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  • MicroRNAs in the Pathogenesis, Treatment and Prevention of Epilepsy

    RCSI

    Principal Investigator: Professor David Henshall, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Which undergraduate disciplines are relevant for this project: Biochemistry, Pharmacology, Physiology, Neuroscience

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    New approaches to the treatment and prevention of epilepsy– a serious, chronic disorder affecting over 60 million people worldwide - are urgently needed. Evidence has emerged that a class of small, non-coding RNA called microRNA is important in the pathogenesis and potential treatment of epilepsy. MicroRNAs control levels of many proteins within cells, functioning...

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  • Investigation and Characterization of the Synaptosome in the Brain in Schizophrenia

    RCSI

    Principal Investigator: Dr Melanie Focking, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Undergraduate disciplines relevant: Neuroscience, Biology, Biochemistry, Molecular
    Biology

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Schizophrenia is a severe psychiatric disorders affecting 1% of the world population. Common treatments are usually untailored and bear the risk of strong side effects. There is an agreed need for targeted treatments which ought to be more effective along with fewer side effects. To achieve this we require a greater understanding of the core...

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  • Cardiovascular and Temperature Effects of Cathinones in Comparison with MDMA

    RCSI

    Principal Investigator: Professor J R Docherty, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Methylenedioxymethamphetamine (MDMA) is a widely used recreational drug of abuse, and a life threatening hyperthermia can occur particularly when the drug is used in a “rave” environment, often with high ambient temperatures and excessive physical exertion, and in combination with other drugs such as caffeine. MDMA has actions at monoaminergic pathways, both peripheral noradrenergic...

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  • Understanding the Basis of Epigenetic Contribution to Brain Changes in Psychosis: the Study of Histone Modification in Schizophrenia, Animal Models of Schizophrenia, and Schizophrenia Derived Neuronal Stem Cells

    RCSI

    Principal Investigator: Professor David Cotter, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    A student interested in proteomics, epigenetics and clinical neuropsychiatry should love this
    project.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Individual genes (G) contribute tiny effect sizes to overall risk for schizophrenia and likewise environmental (E) factors have effect sizes which are small. There is now no question that genetic and environmental risk factors interact to contribute to schizophrenia. The mechanisms underlying these genetic and environmental risk interactions are not known and this is...

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  • Circulating MiRNAs as Biomarkers in Diabetes and Metabolic Syndrome and as Therapeutic Targets

    RCSI

    Principal Investigator: Professor Jochen Prehn, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Research Theme: Diabetes and Endocrinology; MiRNAs are typically 19-25 nucleotide non-coding RNA molecules, which suppress gene expression via imperfect base pairing to the 3’ untranslated region (3’UTR) of target mRNAs, leading to repression of protein production. More than 500 miRNAs in humans have been identified so far which have been estimated to regulate approximately...

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  • Effect of the Central Energy Stress Sensor, AMP-activated Protein Kinase (AMPK), on Neuronal Function and Survival During Ischemic Stroke

    RCSI

    Principal Investigator: Professor Jochen Prehn, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Ischaemic stroke and neurodegenerative disorders are leading causes of death and disability. Because current treatments are limited in their effectiveness, we need to understand more of the underlying pathophysiological processes, and from this, develop new therapeutic strategies. Stroke causes membrane depolarization and an excessive release of excitatory neurotransmitters, in particular glutamate. This opens up...

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  • APOPTO-BRAIN – A Systems Medicine and Patient Stratification Tool for Treatment Decisions in Brain Cancer

    RCSI

    Principal Investigator: Professor Jochen Prehn, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Relevant undergraduate disciplines for this project include: Biochemistry, Genetics, Physiology, Neuroscience, Medicine, Bioengineering, Systems
    biology,

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    The current proposal provides a unique opportunity to achieve significant progress in the emerging field of systems medicine research and personalized medicine approaches in brain cancer. We will perform cutting edge brain cancer research that will explore the role of apoptosis deficiency as a prognostic marker and as a therapeutic target in brain cancer....

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  • Analysis of Non-clinical Respiratory Data for the Presence of Pathologically Striking Artefacts as Precursors to COPD and its Exacerbations with Mobile IT Technology

    RCSI

    Principal Investigator: Professor Kevin McGuigan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Relevant undergraduate disciplines for this project include:
    Medical Physics, Physics, Respiratory Medicine, Computational Science, Engineering

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Chronic pulmonary obstructive disease (COPD) is a common, largely under-diagnosed, complex of various individual symptoms that is associated with significant invalidity, morbidity and mortality. Caused by chronic inflammation or emphysemas of the lungs due to smoking, air pollution, and genetic prevalence, the breathing of the patient becomes increasingly laboured over time . This disease carries...

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  • Developing Model Systems to Investigate the Molecular Mechanisms in Bone Infection

    RCSI

    Principal Investigator: Dr Steve Kerrigan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    The following undergraduate disciplines are relevant for this project: Cell Biology, Biochemistry, Pharmacology, Physiology, Genetics, Biophysics, Biotechnology, Microbiology.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Despite improvements in medical and surgical therapy, osteomyelitis is still associated with a severe prognosis and remains a significant therapeutic challenge. The Host Infection Group in RCSI headed by Dr. Kerrigan is interested in molecular mechanisms that exist between invading pathogens and host cells primarily focusing on Staphylococci and Streptococci interaction with human...

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  • New Class of Light Activated Anti-cancer and Anti-microbial Agents

    RCSI

    Principal Investigator: Professor Donal O'Shea, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Photodynamic therapy (PDT) is a unique treatment modality for a range of disease classes, both cancerous and non-cancerous, which uses low energy light in conjunction with a photosensitizer to effect specific cell death. My research has developed a totally new class of PDT agent, the BF2 chelated dibromotetraarylazadipyrromethenes. Optimised synthetic procedures have been developed...

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  • Platelet Reactivity in a Changing Redox Environment: Implications for Thrombus Formation in Disease States

    RCSI

    Principal Investigator: Dr Sarah O'Neill, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    In many disease states an imbalance between oxidants and anti-oxidants exists. Oxidative stress is manifested as this imbalance and is implicated in the pathogenesis and development of cardiovascular diseases. This precipitates an altered redox status in the vasculature contributing to endothelial dysfunction with subsequent effects on normal platelet function. The consequence is a loss...

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  • New Class of Near-infrared (NIR) Fluorochrome for Real-time Fluorescence Guided Surgery

    RCSI

    Principal Investigator: Professor Donal O'Shea, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    The use of real-time fluorescence imaging has potential in oncology as a guide for surgical resections. As over 50% of all non-skin cancers are first treated with surgery, the benefits of improved surgical outcomes are obvious. The use of longer wavelength NIR fluorochromes circumvents problems of background absorbance and auto-fluorescence from endogenous chromophores, allowing...

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  • Clinical Assessment of Platelet Function During Pregnancy

    RCSI

    Principal Investigator: Professor Niamh Moran, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Background: It is well established that markers of platelet activation are elevated during normal pregnancy. For example, levels of platelet-derived thromboxane are persistently elevated in serum and urine of pregnant women to levels equivalent to those observed in acute cardiovascular disease (Fitzgerald et al. 1987). In addition, other markers of platelet activation such a...

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  • Development of Metal-free Green Process for Enantioselective C-H functionalisation

    RCSI

    Principal Investigator: Professor Mauro Adamo, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Undergraduate disciplines relevant for this project include: Organic synthesis, analytical chemistry.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    This project has been carefully designed to deliver innovative and valuable synthetic and analytical skills. The training components of the project include focus on a variety of specific scientific disciplines, methodologies used in the synthesis and purification of organic compounds, include, controlled atmosphere and temperature reactions, chromatography, 1H-NMR, 13C-NMR, Mass spectroscopy, IR, UV, GC,...

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  • The Role of Platelets in Cancer: An Exploration of the Nature of the Cytokine Secretion Profile in During Cancer Progression

    RCSI

    Principal Investigator: Professor Niamh Moran, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Platelet activation in normal individuals is accompanied by thrombus development and a parallel secretion of bioactive proteins from platelet granules, including inflammatory factors, growth factors, chemokines and cytokines . The precise content of the secretome varies depending on the the physiological or pathological stimulus (Battinelli et al. 2011). We recently demonstrated that isolated cancer cells...

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  • Phase Transfer Catalysed (PTC) Amidation, A Green Cost Efficient Procedure for the Preparation of Peptide Drugs and Valsartan

    RCSI

    Principal Investigator: Professor Mauro Adamo, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Undergraduate disciplines relevant for this project include: Organic synthesis, analytical chemistry.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Aim of this study is the identification of a set of conditions allowing to obtain compounds 25 in yields superior to 90% and in reaction times of 1- 2h maximum. With an optimised set of conditions in hand, we will study the mostgeneral case of coupling that involves aliphatic azides and aliphatic aldehydes, as well...

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  • Functional Analysis of Tumour Suppressor miRNAs in Neuroblastoma Using Preclinical Disease Models

    RCSI

    Principal Investigator: Professor Raymond Stallings, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Neuroblastoma arises from neural crest derived precursor cells of the sympathetic nervous system and is one of the most challenging malignancies of childhood, accounting for 15% of all childhood cancer associated deaths. Thus, the identification of new biological targets that contribute to the aggressive pathogenicity of this disease, along with the development of reagents...

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  • Development of Novel Particulate Drug Delivery Technologies to Target Cardiovascular Infection

    RCSI

    Principal Investigator: Dr Ben Ryan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    This project will aim to build a library of Pt or Ru HDAC inhibitor conjugates with a view to optimising the therapeutic efficacy of the lead candidates already developed. Successful drug candidates will then undergo pharmacological evaluation to establish (i) their effect on HDAC activity, (ii) their ability to bind DNA, (iii) their in...

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  • Polyethylene-like Polymers from Renewable Resources

    RCSI

    Principal Investigator: Dr Andreas Heise, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    A good knowledge of organic chemistry and/or polymer chemistry is required.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Polyethylene is one of the most common materials in our daily lives and accounts for 40% of the total volume of world production of plastic materials. The annual world production is a staggering 80 million tons. The reason is that it is one of the most versatile plastic materials there is and, depending on...

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  • Injectable Chemotherapeutic Gels for the Treatment of Glioblastoma Multiforme

    RCSI

    Principal Investigator: Dr Eduardo Ruiz-Hernandez, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Advanced nanotechnology-based materials offer new solutions to the challenges associated with the non-specific delivery of therapeutics that leads to ineffective treatments, especially in oncology. Currently, both therapeutic and diagnostic molecules are administered systemically, increasing the likelihood of unwanted side effects. We aim to develop a novel delivery system that enables selective, targeted local delivery...

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  • Nanomedicines Against Multi-drug Resistant Pathogens

    RCSI

    Principal Investigator: Professor Marc Devocelle, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Infections caused by antibiotic resistant bacteria have been listed as top priority diseases by the World Health Organisation (WHO) in terms of their threat to global public health if the need for novel medicines is not met. Resistant bacteria have been associated with serious hospital- and community-onset infections, worldwide. Bacterial pathogens exhibiting high-levels of...

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  • Oral Delivery of Biotech Cargoes

    RCSI

    Principal Investigator: Dr Fiona O’Brien, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    There are over 240 protein/peptide drugs marketed worldwide, several hundred in clinical development and even more in preclinical drug discovery pipelines. Delivery of macromolecules by the oral route is restricted by their susceptibility to pre-systemic degradation and poor permeability across the intestinal wall. They must therefore normally be delivered by the parenteral route which...

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  • Nature’s Antibiotic Mimetics

    RCSI

    Principal Investigator: Professor Marc Devocelle, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Undergraduate disciplines relevant for this project include: Chemistry, Microbiology, Pharmacy

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    To apply the peptidomimetic conversion developed by the host laboratory to an optimised AMP candidate. Antimicrobial peptidomimetics and their parent peptide will be synthesised by solution phase and solid phase syntheses,respectively. They will then be tested for their antibacterial (susceptibility testing) and antbiofilm activities (under in vitro static and flow conditions) against a range...

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  • Mannosylation of PLGA microparticles for DNA Vaccine Delivery

    RCSI

    Principal Investigator: Dr Fiona O’Brien, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    To look at the efficacy of this novel branched mannose ligand in the uptake of a DNA polymeric vaccine and its effect on immune system responses. Initially macrophage cell lines will be used to assess uptake studies but further work may include animal models for assessing immune responses. Should the project progress ethical approval...

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  • Development of Novel Metal-based Anti-cancer Chemotherapeutics

    RCSI

    Principal Investigator: Professor Celine J Marmion, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    This project will aim to build a library of Pt or Ru HDAC inhibitor conjugates with a view to optimising the therapeutic efficacy of the lead candidates already developed. Successful drug candidates will then undergo pharmacological evaluation to establish (i) their effect on HDAC activity, (ii) their ability to bind DNA, (iii) their in...

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  • Synthesis and Screening of Novel Analogues of Natural Licochalcones

    RCSI

    Principal Investigator: Dr James Barlow, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    The objective of this research proposal is the synthesis and testing of novel analogues of the prenylated chalcone, licochalcone A, with the aim of gaining a deeper understanding ofthe structure-activity relationships within the family of B-ring prenylated chalcones and cyclic derivatives thereof as (a) potential anti-plasmodial agents and (b) inhibitors of BCRP. Prenylated flavonoids...

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  • Automated Flow Micro-reactors and Parallel Microwave-assisted Synthesis

    RCSI

    Principal Investigator: Professor Donal O'Shea, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Continuous flow chemistry has recently emerged as a productive technology for synthetic pharmaceutical chemists. It offers a new tool to accelerate lead discovery and development as it provides reliable control of reaction conditions, such as time, temperature, equivalents of reagents and mixing, and allows exothermic reactions to be performed without the need for cryogenics....

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  • Bioengineering RNA-nanomedicines to Treat Respiratory Disease

    RCSI

    Principal Investigator: Professor Sally-Ann Cryan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    There is significant clinical and commercial need for new treatments for a range of respiratory conditions (1) including Cystic Fibrosis (CF), Chronic Obstructive Pulmonary Disease (COPD), idiopathic pulmonary fibrosis (IPF), asthma, viral infections e.g. influenza and lung cancer for which current treatments provide only symptomatic control at best but do not treat the genetic...

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  • Mixed Li/K Amides and Enantioselective Carbolithiations as Effective Synthetic Tools

    RCSI

    Principal Investigator: Professor Donal O'Shea, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    We have recently illustrated how mixed Li/K metal TMP amides (LiNK metalation conditions) are uniquely suited for selectively achieving challenging metalations. Specifically, the use of the reagent triad BuLi/KOtBu/TMP(H) to in situ generate a mixed Li/K metal TMP amide has proven to be an efficient and general method to achieve direct vinylic and benzylic...

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  • Cardiovascular Risks to Benefit Balance of Nanoparticles Used in Drug Delivery and Targeting

    RCSI

    Principal Investigator: Dr Sarah O'Neill, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Methylenedioxymethamphetamine (MDMA) is a widely used recreational drug of abuse, and a life threatening hyperthermia can occur particularly when the drug is used in a “rave” environment, often with high ambient temperatures and excessive physical exertion, and in combination with other drugs such as caffeine. MDMA has actions at monoaminergic pathways, both peripheral noradrenergic...

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  • Automated Retrieval and Analysis of Clinical Prediction Rules

    RCSI

    Principal Investigator: Professor Tom Fahey, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Clinical Prediction Rules (CPRs) are used by clinicians to assist them in diagnosis (likelihood of presence/absence of a condition) or prognosis in a patient and have been shown to assist in clinical decision making and improve the process and outcome of clinical care. As an initial stage of incorporating CPRs from research into actual...

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  • Molecular Mechanisms of Farnesoid X Receptor Regulation of Intestinal Epithelial Cells

    RCSI

    Principal Investigator: Dr Stephen Keely, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Intestinal diseases, such as inflammatory bowel disease, irritable bowel syndrome, and infectious diseases are very common in Western societies and represent a huge financial and healthcare burden. The nuclear bile acid receptor, FXR, is expressed in epithelial cells throughout the intestine and in our laboratory we have discovered a new role for this receptor...

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  • MicroRNA Regulation of Innate Immune Responses in the Lung

    RCSI

    Principal Investigator: Professor Catherine Greene, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    MicroRNAs (miRs) are short, endogenous regulatory RNAs that control gene expression at a post-transcriptional phase. miRs have a key role in regulating the expression of genes involved in innate immunity and inflammation1. Sets of miRs can collectively regulate the expression of specific pathways, such that dysregulated miR expression, such as occurs in bronchial epithelial...

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  • Sex-specific Difference in Neonates: Roles of MicroRNA and Toll-like Receptor Signalling

    RCSI

    Principal Investigator: Professor Catherine Greene, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Throughout the neonatal period, males have a poorer disease prognosis compared to females. For example cerebral palsy, meningitis, and neonatal sepsis are more common in males. Post-transcriptional gene regulation by microRNAs and aberrant innate immune mechanisms may play a role in this phenomenon. For example our preliminary studies have (i)identified microRNAs that are detectable...

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  • Long Noncoding RNA Expression and Function in the Cystic Fibrosis Lung

    RCSI

    Principal Investigator: Professor Catherine Greene, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Research focuses on inflammation, innate immunity and chronic inflammatory lung diseases especially cystic fibrosis and alpha-1 antitrypsin deficiency. Long noncoding RNAs (lncRNAs) are a class of RNA molecules for which exciting new roles are emerging in human biology. We have demonstrated that the lncRNA expression profile of bronchial brushings from people with cystic fibrosis...

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  • An Assessment of De-novo Mutations in the Development of Sporadic Epilepsy

    RCSI

    Principal Investigator: Dr Gianpiero Cavalleri, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    This project would be well suited to a student with an interest in genetics, genome sequencing and neurology. Whole genome sequencing is an exciting area of genetics research that is developing rapidly, creating fantastic research opportunities.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Epilepsy encompasses a diverse group of brain disorders characterised by recurrent unprovoked seizures With a lifetime prevalence of between 1-2%, epilepsy is the most common serious disorder of the brain. Six million people in Europe have epilepsy, and approximately 300,000 individuals are diagnosed each year. One third of individuals with epilepsy are refractory to...

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  • Breast Cancer Microcalcification-induced Local Inflammation: Potential Consequences for Tumour Progression

    RCSI

    Principal Investigator: Dr Maria Morgan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Radiographic mammary microcalcifications constitute one of the most important diagnostic markers of both benign and malignant lesions of the breast. Up to 50% of all nonpalpable breast cancers are detected solely through microcalcifications presenting during a mammogram scan and up to 93% of cases of ductal carcinoma in situ (DCIS) present with microcalcifications. During...

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  • Identification of Novel Targets for the Treatment of Methicillin Resistant Staphylococcus Aureus (MRSA)

    RCSI

    Principal Investigator: Dr Marian Brennan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.


    Additional requirements

    Students who have studied any of the Biological sciences, Microbiology, Biochemistry, Chemistry, Genetics or Pharmacology are suited to this project.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    This new exciting project aims to develop compounds for the treatment of MRSA infections. Since the discovery of penicillin, death due to infection has dramatically decreased. Most people have been treated successfully with antibiotics many times in their lives. With this success however has come antimicrobial resistance. Now the challenge is to stay one...

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  • Exosomes Trigger Tumour Resistance to Chemotherapy

    RCSI

    Principal Investigator: Dr Olga Piskareva, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    The acquisition of multidrug resistance by cancer cells involves multiple genetic pathways and is a major impediment to the successful treatment of many forms of this disease. This is particularly true for neuroblastoma, a highly heterogeneous tumour accounting for 15% of all paediatric cancer deaths. Disease recurrence and progression is very common for many...

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  • Osteoporosis: Cellular Response to Estrogen Deficiency and Substrate Stiffness in Three-dimensional In-vivo and In-vitro Environments

    RCSI

    Principal Investigator: Dr Orlaith Brennan, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Osteoporosis is a bone disease that degrades bone mass and architecture and impairs the ability of the skeleton to perform fundamental mechanical functions. As a consequence fractures of the hip, wrist and vertebrae occur and lead to deformity, severe pain and in some cases death. Physiologically, osteoporosis is manifested as an imbalance in bone...

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  • The Inflammatory Platelet and its Role in Inflammatory Bowel Disease (IBD)

    RCSI

    Principal Investigator: Dr Sarah O'Neill, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    Platelet function is altered in conditions such as Inflammatory Bowel Diseases (IBD) and is associated with an increased risk of thromboembolism. This inappropriate activation of platelets in inflammatory conditions is not fully understood. In normal haemostasis, platelets are activated at sites of vascular damage through the interaction of a number of platelet surface receptors...

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  • Examining the Links between Circadian Disruption, Sleep Apnoea and Metabolic Disorders in Professional Drivers

    RCSI

    Principal Investigator: Dr John McDermott, RCSI

    Start Date: Flexible

    Minimum academic requirements

    PhD candidates must normally have obtained at least an upper second class (2.1H) honours degree (or equivalent) in a relevant subject.

    |

    Minimum English Language Requirements

    A high standard of written and spoken English is required.

    The following grades in IELTS and other equivalent English language test scores are accepted

    IELTS : C1 (6.5 – 7.0), C2(7.5 – 9.0),
    Top score: 9

    Cambridge CAE:  C1(Grade A / B / C),
    Top score: 100

    Cambridge CPE:  C1 (Minimum Level C1 (score of 180-199)), C2 (Grade A / B / C),
    Top score: 100

    TOEIC:  C1 (605 – 780), C2 (785 – 990),
    Top score: 990

    TOEFL Paper:  C1 (550 – 587), C2 (590 – 677),
    Top score: 677

    TOEFL CBT:  C1 (213 – 240), C2 (243 – 300),
    Top score: 300

    TOEFL IBT:  C1 (79 – 95), C2 (96 – 120),
    Top score: 120

    (EEA*) Full Time: €6,550 (EEA*) Part Time: €4,370

    (International/Non-EEA) Full Time: €13,100 Part Time: €8,740

    |

    Bench Fees Full Time: €10,000 Part Time: €8,600

    Project Summary

    In western economies, up to 1 in 5 workers undertake shift work involving night work as part of their recurring working arrangements. Given this high number, understanding the health and wellbeing implications of shift work should be of major concern from a public health perspective. Epidemiological evidence indicates that shift work is associated with...

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